Peripheral hepatic sinusoidal obstruction syndrome due to oxaliplatin-based chemotherapy
نویسندگان
چکیده
منابع مشابه
Sinusoidal obstruction syndrome after oxaliplatin-based chemotherapy
Drug-induced liver injury presents with extremely diverse histologic patterns, including necroinflammatory, cholestatic, steatotic and vascular patterns. Sinusoidal obstruction syndrome (SOS), also referred to as toxic sinusoidal injury, veno-occlusive disease or “blue liver syndrome”, is a commonly recognized vascular pattern of drug-induced liver injury, and has been frequently associated wit...
متن کاملSevere hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
BACKGROUND In advanced metastatic colorectal adenocarcinoma, the addition of a neo-adjuvant systemic treatment to surgery might translate into a survival advantage, although this is yet to be confirmed by ongoing randomized trials. The objective of this study was to assess the effects of preoperative systemic chemotherapy on the morphology of non-tumoral liver. PATIENTS AND METHODS A large se...
متن کاملfocal sinusoidal obstruction syndrome caused by oxaliplatin-induced chemotherapy: a case report
conclusions atypical irregular tumors should be considered as sos when the patient has received oxaliplatin-based chemotherapy. a qualitative imaging modality diagnosis, such as with diffusion-weighted mri, is superior to a morphological diagnosis in focal sos. this imaging modality can prevent unnecessary operations. case presentation a 40-year-old woman with rectal cancer underwent high anter...
متن کاملFocal Sinusoidal Obstruction Syndrome Caused by Oxaliplatin-Induced Chemotherapy: A Case Report
INTRODUCTION Sinusoidal obstruction syndrome (SOS) is a severe adverse event of long-term chemotherapy in patients with colorectal cancer. It usually develops as liver congestion due to diffuse microscopic obstruction in liver parenchyma. In contrast, it sometimes appears as a liver mass occurring with local parenchymal hemorrhaging, and is often misdiagnosed as liver metastasis. CASE PRESENT...
متن کاملSevere hepatic sinusoidal obstruction and oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer: a real entity?
We have read with interest the study of Rubbia-Brandt et al. [1] entitled ‘Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer’. In this study, the investigators identified in the specimens from liver resection for colorectal metastases, some histological lesions of the non-tumoral liver parenchyma attributed to oxal...
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ژورنال
عنوان ژورنال: Clinical Case Reports
سال: 2019
ISSN: 2050-0904
DOI: 10.1002/ccr3.1935